Alisson's season ended with a penalty shootout loss, with Darwin Nunez's Uruguay triumphing over Brazil to advance to the Copa America semi-finals.
The contest was a showdown of Liverpool's own in Las Vegas, where Nunez and Alisson vied for a spot in the top four in the early hours of Sunday for UK viewers.
Both players were in their national teams' starting lineups, as they had been throughout the tournament, with a semi-final against Luis Diaz's Colombia at stake.
The game saw few shots on target, with Brazil managing three and Uruguay just one in the 90 minutes.
Alisson made only one save and six recoveries, touching the ball 48 times, ranking ninth in touches on the field according to FotMob.
Nunez, meanwhile, had 28 touches, saw two shots on Alisson's goal blocked, and was substituted in the 78th minute, removing him from the penalty shootout equation.
Brazil's hopes to avoid penalties were raised when Nahitan Nandez received a red card for a harsh tackle, leaving Uruguay with 10 men for the last 16 minutes, but Brazil failed to capitalize.
In the penalty shootout, Alisson's lone save against Jose Gimenez's attempt was insufficient, with Uruguay prevailing 4-2.
After the match, Nunez offered consolation to his Liverpool teammate, sharing words and an embrace before parting ways.
Alisson's season concludes with 40 appearances for club and country, setting his pre-season return for July 29.
Liverpool's number 9, however, will see the Copa America through to the end, returning only after August 5, whether for the final or the third-place match.
