The Liverpool forward struck from the penalty spot in first-half stoppage time to put a Dutch side captained by Virgil van Dijk and also including Ryan Gravenberch two goals to the good against their opponents, who were skippered by Dominik Szoboszlai.
The hosts then added two more goals after the break in Amsterdam, with Gakpo and Gravenberch both substituted around 10 minutes from full-time. Van Dijk and Szoboszlai finished the game.
